7-Keto demonstrates documented thermogenic activity in rats. This is accomplished through the activation of three thermogenic enzymes: Glycerol-3-Phosphate Dehydrogenase, Malic Enzyme and Fatty Acyl CoA Oxidase. In keeping with the biological definition of thermogenesis, all three of these enzyme activations drive energy-producing substrates in a direction of less efficient ATP production relative to heat production. The enzymes also promote the utilization of fat stores for energy and heat production. This is the basis for 7-Keto’s ability to enhance thermogenesis and, through that mechanism, accelerate the utilization of fat stores for energy.
Although the aging process affects all of the segments of the immune system, investigators have identified abnormalities in the cellular, or T-cell, mediated immune function in the elderly. The decline in T-cell immune function is associated with an increased susceptibility to infections. For example, individuals with age-related declines in cellular immunity have an impaired response to influenza vaccine, making them more susceptible to getting the “flu” even though they have had their flu shot.
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